Ruby Blog

Jdrama

2012年我赴日交流，将它视作一个已经成型的发达国家样本；2023年我再到日本交流，看到了曾经繁荣的街区的萧条冷清。日本根据其历史与人民的秉性发展为了自己，虽然与我们绝非相似，但当我们在全世界采...

Posted by brainfo on June 6, 2026

Long Vacation

时隔四年七个月，回国。在过夜的国航飞机上，吃上了热腾腾的饭菜，酒水饮料选项很多。媒体播放器覆盖国内外的影视娱乐资源。我点开了《声生不息》，本只想听歌，但第零期是特别篇，没唱歌，而是讲了下南洋...

Posted by brainfo on June 6, 2026

Zolpidem wakes up coma patients

上维基看到一个列表 wiki；所列11人中有两人服用唑吡坦（思诺思）后醒来，并且“该药物此后被用于唤醒其他昏迷患者,世界各地已有数例被唤醒”。第一例：“路易斯·维尔琼(出生)1970年)19...

Posted by brainfo on April 8, 2026

rejuvenile therapy clinical trial

生物学发展常与阴谋论相伴。在对各大明星返老还童的“科技”阴谋甚嚣尘上之际，所谓细胞返老还童疗法的（小型）一期临床试验已然开始：据clinicaltrials.gov, 试验实际开始于26年3月2...

Posted by brainfo on April 5, 2026

Emotions of LLMs

结论：目前的大语言模型习得了情绪表达，且其情绪会影响其它行为（助手工作）。大家在使用当代模型时，运用文明且适当的表达，不仅避免自己在与模型长期交流后习得暴躁或不礼貌（慎独），也更可能得到自己预期...

Posted by brainfo on April 3, 2026

snRNA-seq based biomedical research

snRNA-seq based biomedical research Case-control studies are commonly adopted in biomedicine res...

Posted by brainfo on February 20, 2026

Trainings for good research

Lessons

I am a PhD student. In essense, this role embodies self development in gaining knowledge and cont...

Posted by brainfo on January 11, 2026

pixi and R in cursor

setup, Mac+Server

cursor on Mac local connected to server. pixi In workspace, pixi init will look for either pixi...

Posted by brainfo on August 27, 2025

visiting Hemholtz Munich

Be courageous to enjoy life

I want this Machine learning, deep learning, and AI should be a part of the toolkits of most bioi...

Posted by brainfo on August 21, 2025

on bulk and pseudo-bulk

practical considerations from personal experiences

This topic was also discussed in a previous post. A preprint questioning pseudo-bulk fidelity M...

Posted by brainfo on July 7, 2025

Brainfo