Here you find the collection of my production

These are supported by variety of funding sources, supervisors, collaborators and fellow students.

• Undergrate thesis
• Master thesis
• PhD thesis
• Publication list

Undergrate thesis

Mainly with the help of Jarning and BioStaCs Lab @USTC

• [基于全基因组测序的线虫突变基因的筛选] (pdfs/基于全基因组测序的线虫突变基因的筛选.pdf)
• in English:[Causal Mutation Screening in C.elegans based on WGS] (pdfs/Causal_Mutation_Screening_in_C.elegans_based_on_WGS.pdf)

Master thesis

• English:Integrating single cell transcriptomic data to track and compare microglias temporal responding of AD and aging process
• 治疗B细胞淋巴瘤的EZH2抑制剂

The following thesis projects were complted with the help of Song Lab and BioStaCs Lab @USTC

• [对基因组三维结构在精子发生和干细胞系中的表征] (pdfs/master_thesis.pdf)

PhD thesis

On going.

• English:Literature review on placenta pathology
• English:Literature review on single cell RNA-seq analysis
• R book:Bookdown discussing topics of single cell RNA-seq analysis

Publication list

1. piRDisease v1. 0: a manually curated database for piRNA associated diseases
2. Epigenomic profiling identifies the role of Nr5a2 and CYP1B1 in hepatocellular carcinoma stemness maintenance
3. Rearrangement of macronucleus chromosomes correspond to TAD-like structures of micronucleus chromosomes in Tetrahymena thermophila
4. Reorganized 3D genome structures support transcriptional regulation in mouse spermatogenesis
5. Transcriptomic survey of key reproductive and metabolic tissues in mouse models of polycystic ovary syndrome
6. Appropriate glycemic management protects the germline but not uterine environment in type 1 diabetes
7. Revealing the molecular landscape of human placenta: a systematic review and meta-analysis of single-cell RNA sequencing studies